Once—daily pill could simplify HIV treatment
Myers Squibb and Gilead Sciences have combined many H．I．V．drugs into a single pill Sometimes the best medicine is more than one kind of medicine．Malaria，tuberculosis and H．I．V．/AIDS，2 for example，are all treated with (1)of drugs．But that can mean a lot of pills to take．It would be____(2)if drug companies combined all the medicines into a single pill，taken just once a day．
Now，two companies say they have done that for people just____(3)treatment for H．I．V．，the virus that canses AIDS．The companies are Bristol-Myers Squibb and Gilead Sciences．They haye____(4)a single pill that combines three drugs currently 0/1the market．3 Bristol—Myers Squibb sells one of them____(5)the name of Sustiva．4 Gilead combined the____(6)，Emtfiva and Viread，into a single．pill in two thousand four．
Combining drugs involves more than____(7)issues．It also involves issues of competition____(8)the drugs are made by different companies．The new once—daily pill is the result of____(9)is escribed as the first joint venture agreement of its kind in the treatment of H．I．V．
In January the New England Journal of Medicine5 published a study of the new pill．Researchers compared its____(10)to6 that of the widely use(combination of Sustiva and ombivir.Combivir____(11)two drugs，AZT7 and 3TC．8 The researchers say that after one year of treatment，the new pill suppressed H．I．V．1evels in more patients and with____(12)side effects．9 Gilead paid for the study．Professor Joel Gallant at the Johns Hopkins School of Medicine in Baltimore，Maryland，led the research．He is a paid adviser to Gilead and Bristol—Meyers Squibb as well as the maker of Combivir，GlaxoSmithKline．
Glaxo Smith Kline reacted____(13)the findings by saying thai：a single study．is of limited value．It says the effectiveness of Combivir has been shown in each of more than fifty studies．
The price of the new once—daily pill has not been announced．But Gilead and Bristol—Myers Squibb say they will provide it at reduced cost to developing countries．They plan in the next few months to ask the United States Food and Drug Administrationlo to—(14)the new pill．
There are limits to who could take it because of the different drugs it contains．For example，____(15)women are told not to take Sustiva because of the risk of bish disorders．11Experts say more than forty million people around the world are living with H．I．V．
词汇：
malaria n．疟疾tuberculosis n．结核(病) j(oint adj．联合的，共同的 suppress
vt．抑制
pregnant aaj．妊娠的，有孕的
注释：
1．HIV(human immunodeficieney virus)：人免疫缺陷病毒
2．AIDS(acquired immunodeficiency syndrome)：获得性免疫缺陷综合征，艾滋病
3．(be／7 come)on the market：出售
4．Sustiva以及后面出现的Emtriva、Viread和Combivir都是治疗艾滋病药物的商品名．
5．New England Journal of Medicine：新荚格兰医药杂志．New England是美国东北六州(Maine，Vermont，New Hampshire.Massachusetts，Rhode Island和Connecticut)的总称．
6．英国英语中compare with是“与…相比较”的意思，compare to是“把…比作…”的意思，但在美国英语中compare t0也有compare with的意思，这里就是“把…与…相比较”的意思．
7．AZT(Azidothymidine)：叠氨胸苷(能抑制引起艾滋病的人免疫缺陷病毒)
8．3TC：拉夫米定(一种胞嘧啶核苷衍生物，能抑制乙肝病毒和人免疫缺陷病毒的逆转录酶的活性，改善肝脏组织的病变)
9．side effect：副作用
10．United States Food and Drug Administration(FDA)：美国食品与药晶管理局
11．birth disorder：先天性疾病
练习：
1．A．conservation
B．eooperation
C．combinations
D．considerations
2．A．simpler
B．more complex
C．more meaningless
D．more troublesome
3．A．starting
B．stopping
C．ending
D．discontinuing
4．A．analyzed
B．examined
C．expiored
D．devekped
5．A．before
B．after
C．under
D．above
6．A．one
B．ones
C．other
D．others
7．A．social
B．technical
C．personal
D．histmqcal
8．A．if
B．as if
C．though
D．as though
9．A．that
B．which
C．what
D．whatever
10．A．size
B．shape
C．appearance
D．effectiveness
11．A．excludes
B．contains
C．looks like
D．tastes of
12．A．few
B fewer
C．many
D．more
13．A．for
B．with
C．to
D．Into
14．A．prove
B．disprove
C．improve
D．approve
15．A．weak
B．strong
C．elder
D．pregnant
1．C．本段中多处提到新药是由几种药合成在一起的，而原来则需要服用多种药物，本空白处四个选项中只有C项“组合物，结合体”是唯一恰当的选择．
2．A．其实，本篇文章的标题就提示了本空白处正确选项．
3．A．这两家研制新药的公司让谁服用这些新药呢?只有A项“开始治疗”的人才有意义，其它三项均不再治疗，那有什么用呢?而且副词just(“即将就要”)也起着帮助选择的作用．
4．D．这两家公司将目前市售的三种药物合成一片，这只能是“开发，研发”(D项)，绝不能是“分析”、“检查”、“探查”．
5．C．这几个介词中，只有under可以与name组合成短语under the name of(“以…名，名为…”)，其它选项在这里均不合适．
6．D．上面提到两家公司已经开发出将多种药合成为单片的新药，Myers公司已合成了一种，Gilead公司则于2004年将其它两种Emtriva和Viread合成为单片，这里既然列出了这两种药的名称，所以就必须用“0thers”．
7．B．合成药物让人们首先想到的自然是“技术”问题，但不仅仅是技术问题，所以下旬就提到竞争问题．
8．A．竞争问题只有当不同药厂制造同一类药品时才会出现，所以只有if才合适．
9．C．本句中，the result of后面应该是一个宾语从句，空白处应该是宾语从句的主语，首先我们可以排除 that和which，因为它们是用来连接定语从句的，其它两个，what=the thing(s)that，whatever=any thing that，两相比较，应该what恰当，因为这里指的是具体这一次，而不是泛指任何一次．
10．D．研究人员对不同药物进行对比，自然是对比它们的疗效，其它三个选项的对比均毫无意义．
11．B．四个选项中只有A和B可以考虑，exclude是“除外，排除”，与contain(“包含，含有”)正相反，因此，即使是不知道AZT和3TC可以治疗艾滋病的人也会选择B项，因为作者绝不会在没有说明AZT和3TC是什么样的药物的请况下就说不包含它们，如果这样就会让读者摸不着头脑．
12．B．既然这种新药可以抑制更多病人的HIV水平，副作用自然应该“更少”，这是使用新药前后的对比，故必须用比较级．
13．C．react to(“对…作出反应”)是固定用法，其它选项均不对．
14．D．从本句字面上看，他们打算在几个月内要求FDA干什么事情呢?而且是与新药有关，而FDA又是审批药品的机关，自然是approve(“批准”)了．
15．D．本句后面已经提到，生育时可能有危险，那就只有孕妇(pregnant women)才有生育的问题了．